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Updated in 2016/11/5 下午 10:31:34      Viewed: 301 times      (Journal Article)
BMC anesthesiology 13 (1): 17 (2013)

Elevated central venous pressure is associated with impairment of microcirculatory blood flow in sepsis: a hypothesis generating post hoc analysis.

Namkje Ar Vellinga , Can Ince , E Christiaan Boerma
Microcirculatory driving pressure is defined as the difference between post-arteriolar and venular pressure. In previous research, an absence of correlation between mean arterial blood pressure (MAP) and microcirculatory perfusion has been observed. However, the microcirculation may be considered as a low pressure compartment with capillary pressure closer to venous than to arterial pressure. From this perspective, it is conceivable that central venous pressure (CVP) plays a more important role in determination of capillary perfusion. We aimed to explore associations between CVP and microcirculatory perfusion.
DOI: 10.1186/1471-2253-13-17