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Updated in 2018/11/1 上午 04:19:48      Viewed: 122 times      (Journal Article)
Science (New York, N.Y.) 231 (4740): 840-3 (1986)

Maturational changes in cerebral function in infants determined by 18FDG positron emission tomography.

H T Chugani , M E Phelps
2-Deoxy-2[18F]fluoro-D-glucose positron emission tomography performed in human infants during development revealed progressive changes in local cerebral glucose utilization. In infants 5 weeks of age and younger, glucose utilization was highest in the sensorimotor cortex, thalamus, midbrain-brainstem, and cerebellar vermis. By 3 months, glucose metabolic activity had increased in the parietal, temporal, and occipital cortices and the basal ganglia, with subsequent increases in frontal and various association regions occurring by 8 months. These functional changes measured with positron emission tomography are in agreement with behavioral, neurophysiological, and anatomical alterations known to occur during infant development.
ISSN: 0036-8075